Evidence Library

エビデンスライブラリ

当サイトの記事で引用されている医学論文・ガイドラインを
エビデンスレベル別に整理しています。

205件の文献

免責事項：本サイトの情報は医療行為（診断・処方・治療）を提供するものではありません。健康上の判断は必ず医師にご相談ください。

エビデンスライブラリ

The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans

Chronic stress and the mitochondria-telomere axis: human evidence for a bioenergetic-debt model of early aging

Effects of exhaustive and/or strenuous exercise on aging-related molecular and physiological biomarkers

The association of serum levels of vitamin D with leucocyte telomere length: A meta-analysis

Epigenetics and gut-brain axis: DNA methylation, aging, and Alzheimer's disease

Effects of NMN Supplementation on Blood Pressure: A Systematic Review and Meta-Analysis

Vitamin B3 derivatives support pancreatic cancer cell survival and chemotherapy resistance

Efficacy of Exosome-Based Therapies for Skin Rejuvenation: A Systematic Review of Human Studies

Continuous glucose monitoring in non-diabetic populations: a systematic review of observational and interventional studies with meta-analysis

Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep

The association between sleep quality and telomere attrition: A systematic review and meta-analysis

Exercise delays aging: evidence from telomeres and telomerase — a systematic review and meta-analysis of RCTs

Topical tretinoin for skin aging: a meta-analysis of randomized controlled trials

Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss: An International Modified Delphi Consensus Statement

Accuracy of Smartwatches in the Detection of Atrial Fibrillation: A Systematic Review and Diagnostic Meta-Analysis

Comparing minoxidil-finasteride mixed solution with minoxidil solution alone for male androgenetic alopecia: a systematic review and meta-analysis of randomized controlled trials

Efficacy and safety of oral minoxidil versus topical solution in androgenetic alopecia: a meta-analysis of randomized clinical trials

Hair graying and melanoma as antagonistic outcomes of melanocyte stem cell stress

Comparative efficacy of topical retinoids for skin aging: a network meta-analysis

Efficacy of hyaluronic acid fillers: a meta-analysis

Sleep patterns and DNA methylation age acceleration in middle-aged and older Chinese adults

Sleep disorders and aging: Mendelian randomization analysis of epigenetic and frailty markers

Effects of Experimental Sleep Deprivation on Peripheral Inflammation: An Updated Meta-Analysis

Poor sleep health is associated with older brain age: the role of systemic inflammation

Growth hormone and aging: a clinical review

Biological aging and lifespan in men and women using a Mendelian randomization study

Effect of Physical Exercise on Telomere Length: Umbrella Review and Meta-Analysis

A Systematic Review and Meta-analysis Highlights a Link Between Aerobic Fitness and Telomere Maintenance

Anthocyanin-enriched pigmented rice promotes healthy ageing through telomere modulation: A randomized clinical trial

Emerging strategies, applications and challenges of targeting NAD+ in the clinic

The Effect of NMN and NR on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis

A pilot study of senolytics to improve cognition and mobility in older adults at risk for Alzheimer's disease

Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results

An unbiased comparison of 14 epigenetic clocks

AP2A1 modulates cell states between senescence and rejuvenation

Targeting Senescence: A Review of Senolytics and Senomorphics

Clinical Frontiers of Exosome Research: A Comprehensive Analysis of Human Trials

Exosomes and Hair Regeneration: A Systematic Review of Clinical Evidence

A Pilot RCT Evaluating the Efficacy of an Exosome-Containing Plant Extract Formulation for Treating Male Alopecia

A systematic review and meta-analysis to investigate the effectiveness of exosome for diabetic wounds

Stem cell-derived exosome treatment for acute spinal cord injury: a systematic review and meta-analysis

The Effect of Exosome Size in PRP on Outcomes in Patients Treated for Knee Osteoarthritis

EAU Guidelines on Sexual and Reproductive Health

2025 IMS Recommendations on menopausal hormone therapy

ホルモン補充療法ガイドライン2025年度版

肺がん検診ガイドライン2025年版

Use of Continuous Glucose Monitoring in Non-diabetic Individuals for Cardiovascular Prevention: A Systematic Review

Non-Invasive Continuous Glucose Monitoring in Patients Without Diabetes: Use in Cardiovascular Prevention

A performance validation of six commercial wrist-worn wearable sleep-tracking devices compared to polysomnography

Diagnostic Accuracy of Apple Watch ECG for Atrial Fibrillation: A Systematic Review and Meta-Analysis

Accuracy and interpretability of smartwatch ECG for early detection of atrial fibrillation: A systematic review and meta-analysis

携帯型/装着型心電計の適切使用に関するコンセンサスステートメント

高齢者医療におけるウェアラブルデバイスの役割と最新の研究動向

A polygenic score for height identifies an unmeasured genetic predisposition among pediatric patients with idiopathic short stature

SGLT2 inhibition eliminates senescent cells

U-shaped association between sleep duration and biological aging

Efficacy of oral NMN supplementation on glucose and lipid metabolism: a systematic review with meta-analysis

The Women's Health Initiative Randomized Trials and Clinical Practice

The urgent need for clear and concise regulations on exosome-based interventions

Oral Minoxidil vs Topical Minoxidil for Male Androgenetic Alopecia: A Randomized Clinical Trial

Human Hair Graying Revisited: Principles, Misconceptions, and Key Research Frontiers

健康づくりのための睡眠ガイド 2023

Exploring the interplay of psychological and biological components of stress response and telomere length

What defines a healthy gut microbiome?

Fecal microbiota transplantation, a tool to transfer healthy longevity

Gut Microbiome in Health and Disease in the Elderly

Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults

Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and NAD+ biosynthesis in healthy, middle-aged Japanese men

Improved Physical Performance Parameters in Patients Taking NMN: A Systematic Review

Epigenetic clocks: a systematic review and meta-analysis

Defining an ageing-related pathology: International Consensus Statement

Targeting Cell Senescence and Senolytics

Exosomes for Treating Hair Loss: A Review of Clinical Studies

細胞外小胞等の臨床応用に関するガイダンス

エクソソーム等に関する事務連絡

Cardiovascular risks associated with different menopausal hormone therapies

Elinzanetant for Vasomotor Symptoms of Menopause

有効性評価に基づくがん検診ガイドライン

The efficacy of using continuous glucose monitoring as a behaviour change tool: a systematic review and meta-analysis of RCTs

令和5年人口動態統計乳幼児突然死症候群（SIDS）統計